Pesquisa sobre:
RECEPTOR, SEROTONIN, 5-HT1D
Descritores Encontrados:
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DeCS
Descritor
Inglês
:
Receptor, Serotonin, 5-HT1D
Descritor
Espanhol
:
Receptor de Serotonina 5-HT1D
Descritor
Português
:
Receptor 5-HT1D de Serotonina
Sinônimos
Inglês
:
Serotonin 1D Receptor
Categoria:
D12.776.543.750.070.800.100.200
D12.776.543.750.100.800.100.200
D12.776.543.750.720.300.800.100.200
D12.776.543.750.720.670.100.750
Definição
Inglês
:
A
serotonin
receptor subtype that is localized to the
CAUDATE NUCLEUS
;
PUTAMEN
; the
NUCLEUS ACCUMBENS
; the
HIPPOCAMPUS
, and the
RAPHE NUCLEI
. It plays a
role
as a terminal autoreceptor that regulates the rate of
SEROTONIN
release from
nerve endings
. This
serotonin
receptor subtype is closely related to and has
similar
drug binding properties as the 5-HT1B RECEPTOR, but is expressed at low levels. It is particularly sensitive to the agonist
SUMATRIPTAN
and may be involved in mediating the drug's antimigrane effect.
Nota Histórica
Inglês
:
2004; use RECEPTOR, SEROTONIN, 5-HT1D (NM) 1996-2003
Qualificadores Permitidos
Inglês
:
AD
administration & dosage
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PH
physiology
RE
radiation effects
TU
therapeutic use
UL
ultrastructure
Número do Registro:
38305
Identificador Único:
D044346
Ocorrência na BVS
:
Similar:
DeCS
CID-10
SciELO
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